ALLANTOIN
AND DERIVATIVES
Dermatological
properties
Allantoin
is a healing, moisturizing, soothing and anti-irritating, keratolytic and
non-toxic agent useful in dermatological, cosmetic and veterinary preparation.
Allantoin is a valuable cell-proliferating healing agent which stimulates
healthy tissue formation. Allantoin has a pronounced keratolytic and skin
softening action, acts as chemical debrider of necrotic and scaling tissue,
cleasing up the areas where applied. Allantoin is effective at quite low
concentrations, 0.1% up to 2%.
As
natural component, Allantoin was found in fetal Allantoic fluid, in wheat
germ, rice polishings, confrey roots, in dog urine and in the urine of
pregnant women, in the earth-worm and as organic component of many soils.
Allantoin
and derivatives
The
amphoteric characteristic of Allantoin permits combination with various
chemical substances to form salts and complexes. In combination with various
therapeutic substance Allantoin sinergizes their activity reducing at same
time their side-effects, sensitizing irritating or toxic properties. The
complex and salts thus formed have been shown to possess useful dermatotherapeutic
properties.
Use
of Allantoin
In
treatment of : skin ulcers, wound, scalds, burns and sunburns, carbuncles,
acne and skin eruptions, fissures and abrasions, impetigo, eczema, psoriasis.
Derivatives
of Allantoin
Aluminium
salts
Combining
astringency of Aluminium and healing effect, minimizing irritations brought
on by the Aluminium salts. For deodorants and antiperspirants, shave products,
skin-astringent lotions, antiacne, foot preparations, veterinary preparations.
AluminiumchlorhydroxyAllantoinate
For
deodorants and antiperspirant ,shave products, skin-astringent lotions,
antiacne.
Use
level : 0,25%after-shave lotions
- 1%-2%antiacne- 0,25% antiperspirant-deodorant
0,25%scalp
preparations- 0,05% to 0,2% mouth washes and tooth pastes
AluminiumdihydroxyAllantoinate
Not
soluble, amphoteric nature acting as antiacid and antiammonia to eliminating
irritating effect, for dusting powder and creams, skin eruptions on children
and infants.
Use
level : 1% to 2%antiacne - 0 ,2%-0,3%
baby preparation-0,1% to2% mouth
washes and tooth pastes
AluminiumchlorhydroxyAllantoinate
propylene glycol
Alcohol
soluble, for high alcohol antiperspirants and deodorants spray, pre-and
after-shave preparations. Use level : 6% to 10% in antiperspirants and
deodorants- 12% to 20%in lotion
creams and powder.
Allantoin
N Acetyl Dl Methionine
Anti
irritant, antidundruff, cleansing and healing scalp conditioners, imparts
elasticity and softness to the hair and lustrous effect, useful in building
up damaged protein molecules of the hair. For hair conditioners, sprays,
hair dressing, shampoos and antidundruff, for nail strengtheners.
Use
level. : 0,2% to 0,5% scalp conditioners-
Allantoin Calcium Pantothenate,
Allantoin Dl Panthenol
For
hair products, to stimulate epithelization, keratinization and healing
of epidermal impaired functions, anti-irritant, hair grooming and lustre
activity, adds high lights to the hairs.
Use
level : 0,2% to 0,4% hair spray
Allantoin
Glycyrrhetinic Acid
Anti-inflammatory
agent with healing and keratolytic properties, for treatment of inflammatory,
allergic pruritic dermatoses, epithelial stimulant, reduces irritation
and sensitization of cosmetics such hair dyes bleaches, hair waving and
hair sprays.
AllantoinPolygalacturonic
Acid
Epithelial
stimulant and detoxifying agent
Use
level : 0,1%to 0,2% moisturizing lotion, cream , body powder and emollient
skin lotion foam
Allantoin
Zincundecylenate
For
fungus infections and epidermophytosis
Allantoin
Ethyl p aminobenzoate
.Combines
local anestetic and antipruritic properties of benzocaine with healing
effect of Allantoin
Use
level : 0,5% to 5% in cream or lotion formulation for treatment of sunburn,
burns and similar dermatological disturbance
Allantoin
Silveracetate
Germicidal
in 2nd and 3rd degree burns, not cause staining of
tissue, useful in surgical glove powders. 1ppm sufficient to kill Pseudomonas
aeruginosa
Use
level : 0,5% to 2% in cream and surgical glove powder
Allantoin
Ascorbate
Hydroquinone
stabilizer in skin bleaching preparations, antioxidant in hair dye preparations,
nitrosamine inhibiting and inactivating , pain relieving in burns
Use
level : 0,4% to 0,5% in antiperspirant gel , cream and spray- 0,3% to 0,5%
as a hypo-allergenic deodorant
Preparations
including Allantoin
hand
lotions and creams
protective
and night cream
sun
and after-sun products
hair
and scalp preparations, hair dressing, gels shampoos
antiperspirants
and deodorant
foot
preparations
talcum
powder
lipsticks
tooth
pastes and mouth washes
shave
and after-shave products
baby
preparations
eye
preparations
rectal
preparations
soaps
and detergents
